117 years without diseases (and with an intestine as a teenager): the hidden secret of the longevity hidden in the DNA of Maria Braryas

Maria Braryas Morera, born in 1907 and died in 2024 at the age of 117, was one of the longest -lived people in the world. His life was the subject of study by a team of Spanish researchers led by Dr. Manel Esteller, specialist in epigenetics, who analyzed his genome and his biological champions to understand the secrets of his longevity.

An exceptional immune system

One of Mary’s strengths was her exceptional immune system. Although he had experienced critical historical events, such as the influence of 1918 and Covid overcome at 113, its cells were still able to effectively react to infections without causing autoimmune inflammation. This allowed the woman to avoid serious diseases such as tumors, heart or neurodegenerative problems, limiting physical disorders to advanced age to some mobility problems and an ear deafness.

Telomers and biological age

One of the surprises of the study concerns the telomers, the ends of the chromosomes that protect DNA and indicate cellular aging. Although Maria’s telomers were shorter than younger people, this did not compromise her health. Scientists suggest that short telomers may have limited the proliferation of cancer, working as a natural protective mechanism. In addition, the epigenetic analysis revealed that its biological age was about 23 years lower than the registry age, an index of healthy longevity.

An intestine as a teenager

Mary’s intestinal microbiota was surprisingly similar to that of a young person. The content of bifidobacterium is high, useful for digestive and metabolic health, thanks also to the daily consumption of three yogurt per day. Its efficient intestine contributed to maintaining low levels of bad cholesterol and good levels of triglycerides, with an optimal mitochondrial function that contrasted oxidation and favored cellular energy.

Life and health habits

Mary followed a Mediterranean diet, smoked or drunk alcohol and maintained an active life, walking daily and cultivating solid social relationships. He loved reading, playing the piano, playing with dogs and spending time with the ultra ninety -year -old daughters. It was precisely this combination of favorable genetics, healthy lifestyle and biological resilience that allowed Maria Braryas Morera to reach 117 years of health.

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