A new Italian technology reproduces the structure of human skin in the laboratory with blood vessels: it could change the future of in vitro research
A artificial skinbut vascularizedfunctional and surprisingly similar to the human one: it is the result of a technology developed in Italy by Bio System Laba startup engaged in the 3D biostampa sector, in collaboration with theUniversity of Padua. The model, created through an innovative three -dimensional process, has just obtained a international patent and it could become one concrete tool to reduce animal tests in workshops around the world.
The fabric was designed to offer a more accurate, reproducible and sustainable alternative to current in vitro experimentation techniques, with important applications in the field dermatological, cosmetic and pharmaceutical. And all this, without resorting to animal experimentation.
A skin with “blood vessels”: thus 3D biostampa replies human physiology
Unlike other models already available, the biostactive skin made by Bio System Lab presents one vascularized structurewhich allows you to keep the fabric alive and vital even for long periods in the laboratory. Thanks to a system of active perfusionwhich simulates the circulation of fluids as in the blood vessels, the tissue manages to absorb nutrients in a constant and uniform way, improving the quality of the tests.
This complex structure includes epidermis and dermisand is designed for replicate precisely the characteristics of human skinboth on a cellular and functional level. The model proposes itself as concrete alternative to the use of animal guinea pigstoday still used despite European regulations, strongly limit their use.
According to a report by Joint Research Center (JRC) Numerous cosmetic tests were conducted of the European Commission between 2010 and 2020 in Europe, despite the formal ban. The lack of reliable alternative models is often cited as one of the main reasons. This biostapped model could fill that void.
A useful model for regenerative medicine, dermatological tests and ethical cosmetics
In addition to reducing the use of animals, biostactive skin can become one Precious tool for research centers and the companies operating in the sectors of the regenerative medicineof the cosmetic development and of the tissue bioengineering. The model allows you to carry out more realistic, customizable and scientifically reliable tests, also on specific treatments for skin diseases or on the response of the tissue to potentially irritating substances.
According to an analysis of Grand View Researchthe global market of 3D biostampa In the medical field it is destined to overcome the 2 billion dollars by 2030driven by the growing need for realistic human models for in vitro experimentation.
The goal of the researchers is now make this technology available on an industrial levelso that it can be integrated into daily research processes, without ethical or environmental compromises. In a context in which science tries to become more and more ethics, sustainable and responsibleeven the skin, in the laboratory, can make a difference.
